Table of Contents
Toggle게놈 번역에 대해서 알아 보겠습니다(한영번역)
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게놈 번역(한국어 원본)Real-Time READ™ 기술을 적용하여 결핵균의 게놈 내 IS6110과 MPB64 DNA를 동시에 증폭한 후 Real-Time PCR로 Mycobacterium tuberculosis (MTB)를 검사하는 제품입니다. IS6110과 MPB64 유전자 검사 결핵균의 분자진단 ● 검사제품의 특징: |
게놈 번역(영어 번역본)Using Real-Time READ™ technology, this product amplifies simultaneously IS6110 and MPB64 genes in tuberculosis bacilli and tests for Mycobacterium tuberculosis (MTB), through Real-Time PCR. Testing for IS6110 & MPB64 genes IS6110 is an insertion sequence present in the MTB genome. As most MBT have one to twenty copies of it, its presence is a useful indicator in tuberculosis tests. There have, however, been reports of MBT strains without this gene, and in such a case, the accuracy of diagnosis can be enhanced by testing simultaneously for IS6110 and MPB64, which is a conserved sequence present in single copy in the MTB genome. This product is designed to detect both genes, significantly improving sensitivity. Molecular detection of MTB Acid-fast bacilli (AFB) smears and culture tests have been conventionally used in the diagnosis of tuberculosis. Although AFB smears are simple and fast, they suffer from low sensitivity and specificity; culture tests are the most accurate among the standard methods, but take a long time, approximately 8 weeks, to produce results. On the other hand, nucleic acid amplification, which has emerged recently as a promising method with the advances in molecular diagnostic technology, detects MTB directly from the sample, and it is being used widely due to its high sensitivity and its ability to produce results quickly. Advantages of the product – Amplifies both IS6110 and MPB64 simultaneously. – Is compatible with a diverse range of sample types, including tissues. – Higher sensitivity than that of nested PCR – Produces results within 3 hours after extraction. – Specialized viewer software is provided to help analysis of the results. |
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이상 서울대학병원에서 의뢰한 게놈 번역(한영번역)의 일부를 살펴 보았습니다.